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Table 4 Multivariable-adjusted ORs and 95% CIs of the HCT2 index quartiles associated with retinopathy of prematurity

From: Association between hematocrit in the first two hours of life and retinopathy during prematurity: a retrospective study from DRYAD

Variable

Unadjusted

Model1

Model2

Model3

 

OR(95%CI)

p value

OR(95%CI)

p value

OR(95%CI)

p value

OR(95%CI)

p value

HCT2

0.83 (0.79 ~ 0.88)

< 0.001

0.91 (0.86 ~ 0.97)

0.004

0.9 (0.84 ~ 0.96)

0.003

0.91 (0.84 ~ 0.97)

0.008

HCT tertiles

        

Q1

Ref

 

Ref

 

Ref

 

Ref

 

Q2

0.27 (0.14 ~ 0.49)

< 0.001

0.45 (0.2 ~ 1.03)

0.057

0.47 (0.2 ~ 1.09)

0.08

0.46 (0.18 ~ 1.15)

0.096

Q3

0.06 (0.02 ~ 0.15)

< 0.001

0.22 (0.08 ~ 0.66)

0.007

0.2 (0.07 ~ 0.63)

0.006

0.23 (0.07 ~ 0.78)

0.018

p for trend

0.25 (0.17 ~ 0.37)

< 0.001

0.47 (0.28 ~ 0.79)

0.004

0.46 (0.27 ~ 0.78)

0.004

0.48 (0.27 ~ 0.86)

0.013

  1. Model 1 adjusts for BW, GA, sex, and delivery mode
  2. Model 2 was adjusted for Model 1 + Multiple Pregnancy + Ans + Apgar1 + Apgar5
  3. Model 3 is adjusted for Model 1 + Model 2 + Etippv + Drccompmeds + Atemp + Surfactant + Pneumothorax + Intub1d + Anytransfusion + Pkbili
  4. Ref, reference; HCT2, hematocrit in the first two hours of life; BW, birth weight; GA, gestational age; Ans, antenatal steroids; Apgar1,1-minute Apgar; Apgar5,5-minute Apgar; Etippv, delivery room intubation and positive pressure ventilation; Drccompmeds, delivery room chest compression and/or resuscitation medication; Atemp, admission temperature in Celsius; Intub1d, intubation within 24 h of life; Any Intub, intubation any time during the NICU stay; Any transfusion, any pRBC transfusion during the NICU stay; Pkbili, peak bilirubin. Q1, Q2 and Q3 are quartiles of HCT2 (hematocrit in the first 2 h of life)