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Table 3 Comparison of clinical and laboratory findings in neonates with culture-proven EOS and LOS in a tertiary care hospital in Sana’a City, Yemen (2020–2021)

From: Comparison of risk factors, clinical characteristics, laboratory findings and bacterial etiology between early-onset and late-onset neonatal sepsis in Sana’a City, Yemen

Findings

EOS (N = 33)

LOS (N = 64)

OR for LOS (95% CI)

P-value

n

(%)

n

(%)

Fever

11

(33.3)

15

(23.4)

0.6 (0.24–1.55)

0.297

Tachypnea

10

(30.3)

32

(50.0)

2.3 (0.95–5.60)

0.064

Grunting

2

(6.1)

4

(6.3)

1.0 (0.17–5.58)

1.000

Retraction

4

(12.1)

18

(28.1)

2.8 (0.87–9.22)

0.075

Cyanosis

4

(12.1)

19

(29.7)

3.1 (0.95–9.91)

0.054

Apnea

2

(6.1)

14

(21.9)

4.3 (1.05–20.40)

0.047

Poor feeding

15

(45.5)

23

(35.9)

0.7 (0.29–1.58)

0.363

Lethargy

16

(48.5)

30

(46.9)

0.9 (0.40–2.17)

0.880

Seizures

3

(9.1)

9

(14.1)

1.6 (0.41–6.51)

0.746

Vomiting

1

(3.0)

10

(15.6)

5.9 (0.72–48.47)

0.092

Diarrheal

1

(3.0)

1

(1.6)

0.5 (0.03–8.39)

1.000

Jaundice

15

(45.5)

12

(18.8)

0.3 (0.11–0.70)

0.005

Edema

1

(3.0)

3

(4.7)

1.6 (0.16–15.75)

1.000

Leukocytosis (> 20 \(\:\times\:\) 103/μl)

6

(18.2)

14

(21.9)

1.3 (0.43–3.65)

0.670

Leukopenia (< 5\(\:\times\:\)103/μl)

2

(6.1)

2

(3.1)

0.5 (0.07–3.72)

0.603

Neutropenia (< 2\(\:\:\times\:\)103 /μl)

4

(12.1)

6

(9.4)

0.8 (0.20–2.87)

0.731

Thrombocytopenia (< 150\(\:\:\times\:\)103/μl)

11

(33.3)

21

(32.8)

1.0 (0.40–2.28)

0.959

Elevated CRP level (> 5 ng/ml)

18

(54.5)

46

(71.9)

2.1 (0.89–5.11)

0.088

  1. EOS early-onset sepsis, LOS late-onset sepsis, OR odds ratio, CI confidence interval, CRP C-reactive protein