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Table 1 Characterization of the variables studied in children enrolled in Municipal Early Childhood Education Centres (n = 112), a municipality south of Minas Gerais, Brazil, 2024

From: Impact of inflammation on anemia in children: a cross-sectional study

Variable

Description N = 112

General characteristics

 Sex

Female

50 (44.6)1

 Age (n = 112)

Months

28.13 ± 7.952

 Ethnicity (n = 85)

White

55 (64.7)1

 Prenatal (n = 112)

Yes

104 (92.9)

 Maternal education (n = 106)

Elementary School

21 (18.8)

 Gestational age (n = 103)

Pre-term

8 (7.8)

 Type of delivery (n = 112)

Caesarean section

35 (33.6)

Dietary habits

 Current breastfeeding (n = 104)

Yes

15 (14.4)1

 Current infant formula (n = 106)

Yes

57 (53.8)1

 Current cow's milk (n = 103)

Yes

71 (68.9)1

 Time exclusive breastfeeding (n = 103)

Months

6 (4.0;6.0)3

 Time total breastfeeding (n = 65)

Months

10 (5.5;14.0)3

 Age at the start of infant formula (n = 53)

Months

4.0 (2.0;7.5)3

 Age of onset of cow's milk (n = 58)

Months

12.0 (7.5;12.0)3

 Use of Iron Supplements (n = 107)

Yes

89 (83.2)1

Health follow-up, socioeconomic status

 Follow-up with a pediatrician (n = 109)

Yes

95 (87.1)1

 Family Health Strategy (n = 107)

Yes

80 (74.7)1

 Cash Transfer Program (n = 109)

Yes

25 (22.9)1

 Family economic situation (n = 112)

 > B2

60 (53.6)1

 Food and Nutritional Insecurity (n = 112)

No

53 (48.2)1

Anthropometric indicators

 BMI/age z score (n = 108)

 < −2 (Thinness)

2 (1.8)1

 

−2 to + 1 (Eutrophy)

67 (62.1)

 

 > + 1 (Overweight)

39 (36.1)

Height/Age z-score (n = 108)

 < −2 (Short stature for age)

27 (25.0)1

Dietary pattern (0–23 months)

 Minimum dietary diversity (n = 39)

Yes

28 (71.0)1

 Minimum frequency of meals (n = 39)

Yes

35 (89.4)1

 Frequency of milk consumption (n = 39)

Yes

26 (66.7)1

 Minimum acceptable diet (n = 39)

Yes

35 (89.4)1

 Egg and/or meat consumption (n = 39)

Yes

31 (79.5)1

 Consumption of sweet drinks (n = 39)

Yes

19 (48.7)1

 Consumption of unhealthy foods (n = 39)

Yes

22 (56.4)1

 Zero vegetable consumption (n = 39)

No

35 (89.7)1

Classification of anemia

 Anemia (n = 112)

Yes

58 (51.8)1

 Microcytic/hypochromic anemia (n = 112)

Yes

20 (17.9)1

 Iron deficiency (n = 112)

Yes

89 (79.5)1

Markers of inflammation

 hsCRP (n = 112)

mg/L

2.05 (0.57; 5.93)3

 Alpha-1 Acid Glycoprotein (n = 112)

g/L

1.30 ± 0.422

Iron profile markers and anemia

  

 Hemoglobin

g/dL

11.07 ± 0.922

 Red blood cells

mm3

4.41 ± 0.362

 MCV (n = 112)

fL

79.90 ± 4.232

 MCHC (n = 112)

g/dL

31.46 ± 0.932

 RDW (n = 112)

%

14.33 ± 1.272

 Ferritin (n = 112)

ng/mL

43.01 ± 24.742

 Iron (n = 112)

μg/dL

55.56 ± 29.632

 Transferrin saturation index (n = 112)

%

14.56 ± 7.742

 Soluble Transferrin Receptor (n = 112)

mg/L

1.23 ± 0.742

 Hepcidin (n = 112)

ng/mL

0.76 ± 0.592

  1. 1N (%), 2 Mean ± SD and 3 Median (interquartile range)
  2. Legend: Anemia: Hemoglobin < 10.9 g/dL for children under 24 months and hemoglobin < 11.4 g/dL for children over 24 months. Microcytic/hypochromic anemia: Hemoglobin < 10.9 g/dL for children under 24 months and hemoglobin < 11.4 g/dL for children over 24 months, MCH < 27.0 pg, MCV < 78.0 fL and MCHC < 34.0 g/dL. Iron deficiency: Microcytic/hypochromic anemia and/or Iron < 40 μg/dL and/or Ferritin < 30.0 ng/mL and/or Soluble transferrin receptor > 1.50 mg/L and/or Transferrin saturation index < 15%