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Table 2 Summary of Results of Multivariate Analysis of Height and Steroid Hormones and HC Dose

From: Growth characteristics of children with 21-hydroxylase deficiency and the value of steroid hormones in height assessment

  

17HOP

AD

T

21DOF

11OHT

11 KAD

11 KT

HC

BA-CAa

b (95%CI)

β

0.014

(0.005 ~ 0.022)**

      

0.104

(0.006 ~ 0.202)*

0.401

      

0.274

SW-males

HBASDS-THSDSb

b (95%CI)

β

    

 − 4.731

(− 9.290 ~ − 0.172)*

− 0.340

   

SW-males

BA-CAb

b (95%CI)

0.032

(0.018 ~ 0.046)***

  

− 0.096

(− 0.177 ~ − 0.014)*

    

β

0.825

  

− 0.423

    

SW-females

BA-CAb

b (95%CI)

      

0.456

(0.144–0.768)**

 

β

      

0.587

 

HSDS-THSDSb

b (95%CI)

 

0.278

(0.119 ~ 0.437)**

      

β

 

0.369

      

BA-CAb

b (95%CI)

0.016

(0.007 ~ 0.024)***

       

β

0.385

       
  1. a2 yr to pre-pubertal
  2. b2 yr to pre-epiphysis closure
  3. *P < 0.05
  4. **P < 0.01
  5. ***P < 0.001