Table 3 Patients with KFD with and without aseptic meningitis or encephalitis
KFD With Aseptic Meningitis or Encephalitis (n = 16) | KFD Without Aseptic Meningitis or Encephalitis (n = 48) | P | |
|---|---|---|---|
Epidemiologic features | |||
Age, yr | 8.0(6.0-11.8) | 10.0(7.0–12.0) | 0.470 |
Male sex | 11(68.8) | 33(68.8) | 1.000 |
Clinical features | |||
Fever (≥ 39℃) | 13(81.3) | 39(81.3) | 1.000 |
Cervical lymph node tenderness | 15(93.8) | 30(62.5) | 0.032 |
Headache | 11(68.8) | 2(4.2) | 0.000 |
Confusion | 6(37.5) | 0 | 0.000 |
Convulsions | 5(31.3) | 0 | 0.000 |
Cutaneous rash | 6(37.5) | 6(12.5) | 0.064 |
Arthralgia | 1(6.3) | 0 | 0.250 |
Hepato-Splenomegaly | 0 | 2(4.2) | 1.000 |
Laboratory features | |||
Leukopenia | 14(87.5) | 23(47.9) | 0.062 |
Increased CRP | 9(56.3) | 8(16.7) | 0.002 |
Increased ESR | 14(87.5) | 30(62.5) | 0.062 |
Elevated liver enzymes | 4(25.0) | 15(31.3) | 0.874 |
Treatment | |||
Corticosteroids | 11(68.8) | 7(14.6) | 0.000 |
IVIG | 10(62.5) | 2(4.2) | 0.000 |