Fig. 2

Microphotographs of SHH-positive gallbladder structures in patient and control samples. (a) Patient sample with numerous (+++) SHH protein-positive cells in the epithelium, few (+) in connective tissue, moderate (++) number of positive cells in blood vessels, and weakly stained numerous (+++w) positive cells in smooth myocytes. SHH IMH, ×200. (b) Control sample with abundant (++++) SHH-positive cells in a small fragment of the epithelium and weakly stained moderate (++w) number of positive cells in connective tissue, blood vessels, and smooth myocytes. SHH IMH, ×200