Fig. 5

Microphotographs of the IGF1-positive gallbladder structures in the patient and control materials. (a) Patient sample with numerous (+++) IGF1-positive cells in the epithelium and abundant (++++) cells in connective tissue and blood vessels but weakly stained abundant (++++w) cells in smooth myocytes. IGF1 IMH, ×200. (b) Control sample with abundant (++++) IGF1-positive cells in the epithelium and blood vessels and numerous (+++) cells in the connective tissue but weakly stained abundant (++++w) smooth myocytes. IGF1 IMH, ×200