Fig. 6

Microphotographs of the IGF1R-positive gallbladder structures in patient and control samples. (a) Patient sample with numerous (+++) IGF1R-positive cells in the epithelium, moderate (++) cells in connective tissue and smooth myocytes, but weakly stained numerous (+++w) cells in blood vessels. IGF1R IMH, ×200. (b) Control sample with abundant (++++) IGF1R-positive cells in the epithelium, connective tissue, blood vessels, and smooth myocytes. IGF1R IMH, ×200