Table 2 Case and control placental histology
Placenta Histology | Cases (n = 74) | Controls (n = 98) | Statistical Analysis | |
|---|---|---|---|---|
Risk Ratio (95% CI) | P value | |||
Placental Weight, grams | 519 (127) | 501 (85) | 0.135 | |
Birth Weight: Placental Weight Ratio (range 5–7) | 7.0 (5.8, 8.1) | 7.2 (6.5, 7.7) | 0.325 | |
Coiling Index (CI) (range 0.1–0.3) | 0.21 (0.10) | 0.20 (0.08) | 0.230 | |
Fetal Vascular Malperfusion | 18 (24%) | 11 (11%) | 1.6 (1.1–2.2) | 0.038 |
Low-Grade | 9 (12%) | * | ||
High-Grade | 9 (12%) | 7 (7%) 5 (5%) | ||
Maternal Vascular | ||||
Malperfusion | 11 (15%) | 25 (26%) | 0.66 (0.4–1.1) | 0.129 |
Mild | 10 (14%) | 25 (26%) | ||
Severe | 1 (1.4%) | 0 (0%) | ||
Chorioamnionitis | 36 (49%) | 28 (29%) | 1.6 (1.1–2.2) | 0.007 |
If yes, FIRS | 22 (61%) | 5 (18%) | ||
FIRS | 2.3 (1.7–3.0)# | 0.001 | ||
Villitis of Unknown Etiology | 9 (12%) | 22 (22%) | 0.6 (0.4–1.1) | 0.061 |
Low-Grade | 6 (8%) | 13 (13%) | ||
High-Grade | 3 (4%) | 9 (9%) | ||
Delayed Villous Maturation | 24 (30%) | 10 (10%) | 2.0 (1.4–2.7) | 0.003 |
Any Placental pathology | 58 (78%) | 68 (69%) | 1.3 (0.9–2.1) | 0.187 |