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Table 1 Baseline characteristics of study populations

From: Gut microbiome dysbiosis as a potential biomarker for liver metabolic disorders in in neonatal hemolytic jaundice

Variables

Treatment group

(n = 62)

Control group

(n = 20)

p-value

Demographic

 Age, days

2.03 ± 0.89

1.86 ± 0.68

0.677

 Male

27 (43.55)

8 (40.00)

0.686

 Gestational age (week)

38.95 ± 1.11

39.35 ± 1.13

0.874

 Birth weight (g)

3392.26 ± 238.60

3498.00 ± 341.09

0.532

Delivery

  

0.122

 Cesarean section

19 (30.65)

10 (50.00)

 

 Vaginal

43 (69.35)

10 (50.00)

 

 Maternal age (year)

30.29 ± 3.44

30.60 ± 3.06

0.582

 Maternal weight (kg)

74.26 ± 10.78

74.20 ± 14.50

0.819

Exclusive breastfeeding

  

0.393

 Yes

2 (3.23)

0 (0.00)

 

 No

60 (96.77)

20 (100.00)

 

Vitro fertilization

  

0.568

 Yes

1 (1.61)

0 (0.00)

 

 No

61 (98.39)

20 (100.00)

 

UCAN

  

0.190

 Yes

4 (6.45)

0 (0.00)

 

 No

58 (93.55)

20 (100.00)

 

Neonatal asphyxia

  

0.190

 Yes

1 (1.61)

0 (0.00)

 

 No

61 (98.39)

20 (100.00)

 

Clinical variables

 ALT, U/L

15.264 ± 2.33

18.05 ± 4.03

0.672

 AST, U/L

65.68 ± 7.07

20.43 ± 8.17

0.006

 CRP, mg/L

5.74 ± 1.26

2.37 ± 1.51

0.032

 PCT, ng/mL

1.28 ± 0.93

1.09 ± 0.86

0.872

 WBC, 109/L

14.56 ± 2.03

15.47 ± 5.92

0.562

 NEU, %

60.05 ± 5.16

63.60 ± 9.79

0.598

 TBIL, μmol/L

223.76 ± 52.09

97. 99 ± 26.68

 < 0.001

 DBIL, μmol/L

33.76 ± 2.24

7.00 ± 1.23

 < 0.001

  1. Data presented as n (%), mean ± standard deviation
  2. ALT alanine aminotransferase, AST aspartate transaminase, CRP C-reaction protein, PCT procalcitonin, WBC white blood cell, UCAN umbilical cord around the neck, NEU Neutrophil, TBIL total bilirubin, DBIL direct bilirubin