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Table 5 Comparison of clinical data of different groups with obesity

From: Genetic etiology and clinical features of non-syndromic pediatric obesity in the Chinese population: a large cohort study

Group

Positive(n = 32)

Negative(n = 359)

Z/t Value

P

Age

10.50 ± 1.67

10.34 ± 1.74

0.258

0.612

BA

12.01 ± 1.69

11.44 ± 2.53

1.294

0.256

Wt

62.13 ± 14.96

59.25 ± 14.33

1.176

0.279

Ht

150.51 ± 11.67

147.33 ± 11.05

2.409

0.121

BMI

27.01 ± 3.21

26.90 ± 3.44

0.031

0.861

Wt-Z value

3.26 ± 0.84

3.19 ± 0.97

0.087

0.768

Ht-Z value

1.29 ± 0.90

1.76 ± 13.39

0.039

0.844

BMI-Z value

2.89 ± 0.62

2.99 ± 0.72

0.583

0.446

WC

86.47 ± 9.54

86.29 ± 10.07

0.009

0.924

HC

95.58 ± 8.31

92.62 ± 9.77

2.506

0.114

Urinary microprotein

(mg/L)

22.03 ± 51.07

11.68 ± 17.77

5.88

0.016*

T(ng/dl)

38.83 ± 54.29

45.87 ± 69.46

0.281

0.596

IGF−1

277.77 ± 128.08

274.69 ± 142.90

0.011

0.918

IGF-BP3

6.25 ± 1.74

5.56 ± 1.78

3.469

0.063

ACTH

16.23 ± 17.03

13.04 ± 7.64

3.402

0.066

25-OH-VD

53.48 ± 12.72

59.79 ± 31.42

1.11

0.293

FT3

4.20 ± 0.70

4.30 ± 0.53

0.835

0.361

FT4

1.41 ± 0.63

1.28 ± 0.24

5.49

0.020*

TSH

2.88 ± 1.16

2.62 ± 1.38

0.919

0.338

ALT

55.72 ± 50.75

40.51 ± 37.32

4.184

0.042*

AST

39.62 ± 22.80

33.72 ± 18.38

2.653

0.104

ALP

278.66 ± 72.88

287.86 ± 167.01

0.087

0.769

GGT

35.28 ± 36.78

24.25 ± 19.50

7.179

0.008**

LDH

269.61 ± 57.82

262.03 ± 50.59

0.566

0.452

Uric acid

446.31 ± 117.47

409.92 ± 89.95

4.159

0.042*

FFA(0.4–0.9)

0.74 ± 0.30

0.70 ± 0.28

0.657

0.418

Serum phosphorus

1.72 ± 0.23

1.64 ± 0.20

4.501

0.035*

Father Ht(cm)

169.62 ± 5.12

172.25 ± 55.57

0.058

0.809

Father Wt(kg)

102.22 ± 145.01

76.47 ± 41.22

5.014

0.026*

Father BMI

25.42 ± 2.67

25.85 ± 4.34

0.238

0.626

Mother Ht(cm)

158.83 ± 4.94

158.10 ± 8.61

0.182

0.67

Mother Wt(kg)

60.90 ± 9.55

58.98 ± 9.84

0.881

0.349

Mother BMI

24.09 ± 3.77

23.47 ± 3.53

0.707

0.401

IGT

1.66 ± 0.48

1.82 ± 0.39

4.962

0.026*

HbA1c

5.14 ± 0.63

4.96 ± 0.56

3.009

0.084

HDL-C

1.78 ± 0.42

1.79 ± 0.41

0.015

0.902

non-HDL-C

1.75 ± 0.44

1.91 ± 0.29

7.941

0.005**

  1. Note: * P < 0.05 **P < 0.01
  2. Abbreviations: BA: bone age; Wt: weight; Ht: Height; BMI: Body mass index; WC: Waist circumference; HC: Hip circumference; T:Testosterone; IGF−1:Insulin-like growth factor−1;IGF-BP3: insulin-like growth factor binding protein−3;ACTH: Adrenocorticotropic Hormone;25-OH-VD:25-Hydroxyvitamin D; FT3:free triiodothyronine; FT4:free thyroxine; TSH: thyroid stimulating hormone; ALT: alanine aminotransferase; AST: Aspartate Aminotransferase; alkaline phosphatase (ALP); GGT: gamma-glutamyl transferase; LDH: lactate dehydrogenase; FFA: Free Fatty Acids; IGT: Impaired Glucose Tolerance; HbA1c: Glycated hemoglobin; HDL-C: high-density lipoprotein cholesterol
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BMC Pediatrics

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