Table 4 Changes in sex hormones after treatment note: the paired t-test was used to compare the hormone levels in each treatment period with those at the beginning of combined treatment. *:P < 0.05; **:P < 0.01. FSH: follicle-stimulating hormone; LH: luteinizing hormone; E2: estradiol; T: testosterone

Diagnosis of CPP

2.1(1.5-3.0)

1.2(0.8–1.4)

13.0(10.3–15.5)

22.0(12.8–50.5)

GnRHa treatment period

0.4(0.1–0.6) *

0.2(0.1–0.4) *

5.5(4.2–15.2)

11.3(11.1–22.1) *

End of GnRHa treatment

1.9(1.6–3.2)

1.1(1.0-1.7)

35.5(25.5–50.3)

17.0(10.7–20.8)

Anastrozole treatment period

2.2(1.7–2.8)

1.2(1.3–1.8)

6.5(5.7–13.6) **

30.3(25.0-60.2)