Table 5 Postoperative treatment, length of hospital stay, and follow-up period of patients with perforated peptic ulcer

Bülbül and Şalcı, 2024. [15]

Laparotomy (n = 11, 100%)

N/A

7 (4–10)

3 (0–24)

Wang et al., 2023. [16]

Laparoscopy (n = 19, 63.3%),

laparotomy (n = 11, 36.7%)

N/A

Laparoscopy (13.8 ± 15.2)

Laparotomy (16.1 ± 18.9)

N/A

Shen et al., 2023. [17]

Laparotomy (n = 9, 69.2%),

laparoscopy (n = 4, 30.8%)

N/A

Surgery group (13.6 ± 5.60)

Conservative group (14.8 ± 4.60)

8 (6–24)

Sayan et al., 2021. [18]

Laparotomy (n = 9, 100%)

N/A

N/A

The mean postoperative follow-up period of the patients was 11.8 months.

No complications or recurrence were observed.

Yan et al., 2019. [19]

Laparotomy (n = 13, 65%),

laparoscopy (n = 7, 35%)

N/A

8 (7.0–9.3);

gastric localization (8.5 ± 2.2), duodenal localization (12.5 ± 4.0)

The mean follow-up period was 18.5 months.

No complications or recurrence were observed.

Reusens et al., 2016. [20]

Laparoscopy (n = 5, 100%)

All patients (n = 5) received general postoperative treatment, which consisted of antalgic treatment, antibiotics (cefazoline), and PPI.

6 (4–12)

N/A

Wong et al., 2015. [21]

Laparoscopy (n = 7, 53.8%),

laparotomy (n = 6, 46.2%)

6 weeks after the initial surgery, upper endoscopy was performed in all patients (n = 13)

From all patients (n = 13) antral biopsy was taken.

H. pylori (n = 2); successfully treated with eradication therapy (clarithromycin, amoxicillin, and PPI).

Laparoscopic group (6.4 ± 1.5)

Laparotomic group (10.3 ± 4.4)

N/A

Yildiz et al., 2014. [22]

Laparotomy (n = 9, 100%)

Triple therapy for H. pylori eradication; amoxicillin 50 mg/ kg/day, lansoprazole 1 mg/kg/day, and clarithromycin 15 mg/kg/day for 2 weeks

N/A

58 (3–94);

abdominal pain 2 years after the therapy (n = 1) (patient was administered a repeat course of conservative medical therapy)

Hua et al., 2007. [23]

Laparotomy (n = 51, 98.1%),

laparoscopy (n = 1, 1.9%)

H2 blocker or proton pump inhibitor (PPI) n = 12)

N/A

44 (84.6%) were available for follow-up.

22 had abdominal pain after the PPU episode and 6 patients had PUD recurrence confirmed by endoscopy. All of the patients with recurrent PUD were managed by ‘‘classic’’ surgery and 3 were given postoperative antacid treatment. No patient had PPU again

Wong et al., 2006. [24]

Laparoscopy (n = 13, 76.5%),

laparotomy (n = 4, 23.5%)

Patients with H. pylori (n = 16) received triple antibiotic therapy (PPI, clarithromycin, and amoxicillin)

The median was 7 days

The median was 32.6 months

Edwards et al., 2005. [25]

Laparotomy (n = 16, 100%)

N/A

N/A

N/A

Dunn et al., 1983. [26]

Laparotomy (n = 12, 100%)

N/A

N/A

N/A