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Table 2 Population demographics and baseline information of surviving and deceased children with moderate-to-severe ARDS and hematologic or immune-related diseases

From: Risk factors for mortality in children with moderate-to-severe ARDS with concurrent hematological or immune-related diseases: a retrospective analysis

 

Surviving group (n = 22)

Deceased group (n = 43)

x²/Z

p

Male/Female, n

12/10

22/21

0.067

0.796

Age, median and quartile, m

75(18,100)

30(6,88)

-1.180

0.238

Age<6 years old

10(45.5)

31(72.1)

4.434

0.035

Weight, median and quartile, kg

17.0(10.4,29.3)

12.0(8.0,20.0)

-1.318

0.188

WAZ, median and quartile

-0.52(-1.40,0.725)

-0.43(-0.20,0.18)

-0.053

0.958

PIM3, median and quartile

13.5(5.6,86.7)

23.1(7.8,90.2)

-1.192

0.233

PELOD2, median and quartile

5(2,9)

8(5,12)

-2.237

0.025

OI, median and quartile

9.98(8.58,21.41)

16.80(11.00,26.33)

-2.218

0.027

Sever PARDS, n(%)

8(36.4)

24(55.8)

2.203

0.138

Septic Shock, n(%)

3(13.6)

20(46.)

6.880

0.009

Neutropenia, n%

5(22.7)

19(44.2)

2.878

0.090

Invasive Fungal Infections, n(%)

5(22.7)

22(53.5)

5.616

0.018

HSCT, n(%)

1(4.5)

4(9.3)

/

0.496

Primary Diseases

    

 PID

6(27.3)

12(27.9)

0.003

0.957

 Leukemia

4(18.2)

13(30.2)

1.094

0.296

 Lymphoma

1(4.5)

7(16.3)

/

0.248

 SLE

4(18.2)

0(0)

/

0.011

 MA

0(0)

6(14.0)

/

0.088

 AA

0(0)

2(4.7)

/

0.545

 JIA

3(13.6)

1(2.3)

/

0.109

 Other*

4(18.2)

2(4.7)

/

0.168

Examination

    

 WBC (×109/L)

8.43(6.18,16.63)

8.45(1.09,22.47)

-0.094

0.925

 PCT (×109/L)

0.77(0.38,2.94)

2.22(0.54,4.86)

-1.365

0.172

 Creatine, µmol/L

26.0(19.4,67.0)

33.0(20.5,40.0)

-0.247

0.805

 Lactate, mmol/L

1.0(0.6,1.9)

0.7(0.5,1.8)

-0.584

0.559

 PaO2, mmHg

62.3(52.3,84.0)

60.0(50.0,75.6)

-0.603

0.546

 PaCO2, mmHg

38.5(32.8,51.4)

48.0(37.7,60.0)

-1.754

0.079

 Glucose, mmol/L

6.8(5.1,7.6)

5.94.8,7.7)

-0.488

0.626

 Positive Blood Pathogen, n(%)

8(36.4)

13(30.2)

0.250

0.617

 Positive Sputum Pathogen, n(%)

18(881.)

31(72.7)

0.742

0.389

  1. WAZ, weight-for-age z-score; PIM3, Pediatric Index of Mortality 3 score; PELOD2, Pediatric Logistic Organ Dysfunction 2 score; HSCT, Hematopoietic Stem Cell Transplantation; OI, oxygenation Index; PID, primary immunodeficiency diseases; SLE, systemic lupus erythematosus; MA, Mediterranean anemia; AA, aplastic anemia; JIA, juvenile idiopathic arthritis; PaO2, partial pressure of oxygen of arterial blood; PaCO2: partial pressure of carbon dioxide of arterial blood;
  2. *Other: 1myelodysplastic syndromes,1 idiopathic thrombocytopenic purpura,1 acquired immune deficiency syndrome, 1 Behcet’ syndrome, 1 hemophagocytic lymphohistiocytosis, 1 Autoimmune hemolytic anemia