Fig. 2

WGCNA analysis of the GSE100154 dataset (KD vs. control). (a) Network topology for different values of the soft-threshold power, and selection of a β value of 18. (b) Gene clustering dendrogram, with different colors indicating distinct clusters. Thirteen modules had similar co-expression characteristics. (c) Heatmap for the correlation of different modules with disease phenotype. The pink and purple modules had positive correlations with KD, while the green-yellow and turquoise were negatively correlated