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  1. This study aimed to investigate the perceived safety during the transfer process of infants from a Neonatal Intensive Care Unit (NICU) to a regional level II department. It sought to identify stakeholder agree...

    Authors: Karen de Bijl-Marcus, Fenna Mossel, Kees Ahaus, Bettine Pluut, Manon Benders, Arjan Bruintjes and Martina Buljac-Samardzic
    Citation: BMC Pediatrics 2025 25:211
    Content type: Research Published on:

  2. Sepsis is a major cause of neonatal mortality worldwide. However, its risk factors, clinical characteristics, laboratory findings, and bacterial etiology vary across countries. Therefore, this study compared t...

    Authors: Mohammed Al-Shehab, Rashad Abdul-Ghani, Muna Elnemr, Farouk Al-Qadasi, Ghassan Alabsi, Waleed Farie and Yahya Alghafari
    Citation: BMC Pediatrics 2025 25:208
    Content type: Research Published on:

  3. Exclusive enteral nutrition (EEN) is recommended as first-line therapy for children with mild to moderate Crohn’s disease (CD), given its effectiveness in inducing clinical remission (CR) and promoting mucosal...

    Authors: Yudie Hu, Yao Lv, Jingan Lou, Youyou Luo, Gan Yang, Yang Liu, Jiaying Zhou, Changjun Zhen, Jindan Yu, Youhong Fang, Hong Zhao, Kerong Peng, Yan Ni and Jie Chen
    Citation: BMC Pediatrics 2025 25:206
    Content type: Research Published on:

  4. Pneumococcal meningitis is a central nervous system infection responsible for high rates of mortality and long-term disability worldwide. We aimed to summarise the clinical characteristics, as well as determin...

    Authors: Yixuan Li, Binglin Jian, Xuekai Kang, Mengjie Zhang, Lingyun Guo, Xue Ning, Liang Zhu, Tianming Chen, Bing Hu, ShuPing Liu, Haijuan Xiao, Xin Guo, Wenya Feng, Zhenzhen Dou, Linlin Liu, Qinjing Li…
    Citation: BMC Pediatrics 2025 25:205
    Content type: Research Published on:

  5. High-risk neuroblastoma (HR-NB) is associated with high metastatic and relapse rates that require intensive multimodal treatment. We evaluated the efficacy and safety of dinutuximab beta as first-line maintena...

    Authors: Xuedi Yu, Suyi Kang, Junjie Ge and Jingfu Wang
    Citation: BMC Pediatrics 2025 25:203
    Content type: Research Published on:

  6. Short efficient questionnaires to detect depressive symptoms in adolescents are sparsely evaluated. We aimed to examine the test–retest reliability and structural and convergent validity of the Danish version ...

    Authors: Christine Leonhard Birk Sørensen, Therese Koops Grønborg and Karin Biering
    Citation: BMC Pediatrics 2025 25:201
    Content type: Research Published on:

  7. COVID-19 has become a global pandemic. However, studies examining the outcomes for pediatric patients after hospital discharge, post-COVID-19, and the predictive factors influencing their high mortality rates,...

    Authors: Izzah Baridah, Dwi Kisworo Setyowireni, Arsitya Nayana Citta and Eggi Arguni
    Citation: BMC Pediatrics 2025 25:199
    Content type: Research Published on:

  8. Children born small for gestational age (SGA) have shown an increased risk of developing cognitive impairment and more difficulties regarding academic performance later in life. However, it is not known whethe...

    Authors: Ida Kongstad and Suzanne Petersson
    Citation: BMC Pediatrics 2025 25:196
    Content type: Research Published on:

  9. Whether intraoperative isotonic balanced maintenance fluid is associated with less variation in sodium homeostasis in small children undergoing major neurosurgery remains unknown.

    Authors: Mao-Wei Xing, Yue Zhang, Hui-Ting Zhu, Chang Liu, Zhi-Yu Geng, Lin-Lin Song and Dong-Xin Wang
    Citation: BMC Pediatrics 2025 25:195
    Content type: Research Published on:

  10. The Omicron variant of SARS-CoV-2 has been associated with unique clinical presentations in children, including croup-like symptoms such as barking cough, hoarseness, and respiratory distress. This study aimed...

    Authors: Fatemeh Pourjoula, Seyed Hossein Mirlohi and Niloufar Ghanbari
    Citation: BMC Pediatrics 2025 25:194
    Content type: Research Published on:

  11. Pediatric healthcare professionals facilitate children to enhance and maintain a physically active lifestyle. Activity monitors (AM) can help pediatric healthcare professionals assess physical activity in ever...

    Authors: Barbara Engels, Manon A. T. Bloemen, Richard Felius, Karlijn Damen, Eline A. M. Bolster, Harriët Wittink, Raoul H. H. Engelbert and Jan Willem Gorter
    Citation: BMC Pediatrics 2025 25:193
    Content type: Research Published on:

  12. The article presents a case report of subacute epiglottitis in a healthy three-year-old child, secondary to Epstein-Barr Virus (EBV) infection. This case is particularly significant as EBV-related epiglottitis...

    Authors: Sharareh Babaei and Azin Momeni
    Citation: BMC Pediatrics 2025 25:192
    Content type: Case Report Published on:

  13. Evidence suggests maternal birth experience impacts infant health. Alterations of the infant’s hypothalamus-pituitary-adrenal (HPA) axis are discussed as one possible underlying mechanism. This study aimed to ...

    Authors: Isabel Jaramillo, Luisa Bergunde, Corinna Müller-Stark, Marlene Karl, Victoria Weise, Clemens Kirschbaum, Susan Garthus-Niegel and Susann Steudte-Schmiedgen
    Citation: BMC Pediatrics 2025 25:191
    Content type: Research Published on:

  14. This study aimed to assess the potential of thrombospondin 1 (TBS-1) as a biomarker for pediatric-onset systemic lupus erythematosus (pSLE) and investigated its association with clinical characteristics and ot...

    Authors: Chenxi Liu, Menglan Zhang, Lingyi Yan, Jie Luo, Zhijun Liu, Ting Liu and Yongmei Jiang
    Citation: BMC Pediatrics 2025 25:190
    Content type: Research Published on:

  15. The Sustainable Development Goals (SDGs) prioritize optimal early childhood development (ECD) for all children, emphasizing the principle of leaving no one behind. Despite this focus, the association between d...

    Authors: Shimlin Jahan Khanam, Badsha Alam, Awal Kabir and Nuruzzaman Khan
    Citation: BMC Pediatrics 2025 25:189
    Content type: Research Published on:

    The Correction to this article has been published in BMC Pediatrics 2025 25:232

  16. Authors: Fatemeh Sadat Hashemi Javaheri, Zahra Mousavi, Saeideh Mohammadi, Arezoo Amjadi, Khadijeh Abbasi Mobarakeh, Seyedeh Hayedeh Mousavi Shalmani, Mahdieh Torkaman, Masoomeh Alsadat Mirshafaei, Sara Khoshdooz, Zahra Saeedirad, Naser Kalantari, Parmis Mirzaei, Saeid Doaei, Nastaran Keshavarz Mohammadi and Maryam Gholamalizadeh
    Citation: BMC Pediatrics 2025 25:188
    Content type: Correction Published on:

    The original article was published in BMC Pediatrics 2025 25:67

  17. This study aimed to investigate the relationship between body mass index (BMI) during adolescence and the future risk of developing hypertension, with a particular focus on potential sex differences.

    Authors: Rongtian Liu, Haofei Hu, Changchun Cao, Yong han, Yuxin Bai and Wei Feng
    Citation: BMC Pediatrics 2025 25:187
    Content type: Research Published on:

  18. Globally, gastroenteritis stands as a primary contributor to child mortality, annually taking the lives of 3 million children under the age of 5 years. Rotavirus, a major factor in viral diarrhea among childre...

    Authors: Behrooz Heydari, Majid Aflatonian, Mina Bagherizadeh, Farahnaz Hoseinzade and Fatemeh Saghafi
    Citation: BMC Pediatrics 2025 25:186
    Content type: Research Published on:

  19. Primary pulmonary rhabdomyosarcoma (RMS), a rare soft tissue sarcoma, is characterized by a high recurrence rate and a poor prognosis. This systematic review aims to summarize the clinical characteristics, pat...

    Authors: Yinjie Tao, Weishi Cheng, Hongnan Zhen, Jing Shen, Hui Guan and Zhikai Liu
    Citation: BMC Pediatrics 2025 25:185
    Content type: Research Published on:

  20. Despite efforts to improve neonatal care worldwide, neonatal mortality rates in sub-Saharan Africa remain high. Adequate space, equipment, and staff are vital to improving mortality rates through high-quality ...

    Authors: Mc Geofrey Mvula, Moses Banda Aron, Isaac Mphande, Lemekeza Namwali, Lawrence Nazimera, Martha Kusamba, Enoch Ndarama, Paul Sonenthal, Alden Hooper Blair, Kimberly Baltzell, Fabien Munyaneza, Chiyembekezo Kachimanga, Beatrice Matanje and Emilia Connolly
    Citation: BMC Pediatrics 2025 25:184
    Content type: Research Published on:

  21. Limited options are available to evaluate children's feelings about healthcare during hospitalization. Among the few tools available, this study aimed to extract children's experiences of hospitalization throu...

    Authors: Lida Abazari, Asma Ghonchehpour, Aida Abazari, Zahra Isari, Mohammad Hossein Abbaszadeh and Asghar Tavan
    Citation: BMC Pediatrics 2025 25:183
    Content type: Research Published on:

  22. Pneumonia is one of the major causes of morbidity and mortality among under-five years old children’s worldwide, with Ethiopia having the highest rates among Sub-Saharan African nations. Effective control and ...

    Authors: Kidist Asrat Degif, Mulat Gebrehiwot, Garedew Tadege, Lidetu Demoze and Gelila Yitageasu
    Citation: BMC Pediatrics 2025 25:182
    Content type: Research Published on:

  23. Hemolytic uremic syndrome (HUS), characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury (AKI), remains a leading cause of pediatric AKI. The complement system...

    Authors: Petra Varga, Erika Biró, Andrea Berkes, Erzsébet Lakatos, Edit Szikszay, Zoltán Prohászka and Tamás Szabó
    Citation: BMC Pediatrics 2025 25:181
    Content type: Case Report Published on:

  25. Cytomegalovirus (CMV) infection poses risks to both maternal and neonatal health, however there are limited comprehensive data on congenital CMV in low-resource settings where the virus is widespread, particul...

    Authors: Noela Regina Akwi Okalany, Ingunn Marie S. Engebretsen, David Mukunya, Martin Chebet, Francis Okello, Andrew D. Weeks, Edrin Mwanda, Rita Muhindo, Fred Bisso, Thorkild Tylleskär, Peter Olupot-Olupot and Kathy Burgoine
    Citation: BMC Pediatrics 2025 25:179
    Content type: Research Published on:

  26. Histiocytic sarcoma as a secondary malignancy following childhood leukemia is extremely uncommon with fewer than 20 cases reported worldwide. They often pose a diagnostic challenge and prognosis is dismal. The...

    Authors: Sue Lyn Tan, Betty Lee Sue Ho, Ting Ting Yew and Dahziela Yunus
    Citation: BMC Pediatrics 2025 25:178
    Content type: Case Report Published on:

  27. Turner syndrome (TS) is one of the important causes of short stature in girls, but there are cases of misdiagnosis and missed diagnosis in clinical practice. Our aim is to analyze the hand skeletal characteris...

    Authors: Yirou Wang, Yumo Wang, Feihan Hu, Liqi Zhou, Yu Ding, Chen Guo, Yao Chen, Yabin Hu, Shijian Liu and Xiumin Wang
    Citation: BMC Pediatrics 2025 25:177
    Content type: Research Published on:

  29. Hepatitis B is a major global health concern, with chronic infections affecting approximately 296 million people yearly. A 2009 survey in East Africa showed a prevalence rate of 6.5%, with Uganda’s rate at 10....

    Authors: Andrew Kimera, Joseph Rujumba, Cynthia Kuteesa Ndikuno, Grace Ndeezi, Nelson Mukiza, Andrew Basenero, Theresa Piloya, Sabrina Bakeera-Kitaka, Rebecca Nabulya, Anna Maria Nalumansi, Agnes Namagembe, Irene Bagala, Agatha Namutosi, Esther Kobel, Zakia Bazaali, Caroline Nansubuga…
    Citation: BMC Pediatrics 2025 25:175
    Content type: Research Published on:

  30. Understanding the impact of the COVID-19 pandemic on child survival is crucial. Analysing COVID-19-related child deaths, even years after the pandemic, is critical for informing future pandemic preparedness an...

    Authors: Kapila Jayaratne, Poojani Illangasinghe, Suvini Wanniarachchi, Dilka Hettiarachchi, Chithramalee de Silva and Guwani Liyanage
    Citation: BMC Pediatrics 2025 25:174
    Content type: Research Published on:

  31. Studies on physical activity (PA) and sedentary behavior (SB) patterns contribute to planning specifically-population-targeted health interventions. However, most do not assess PA and SB based on types. The cu...

    Authors: Lizziane Andrade Dias, Gilmar Mercês de Jesus and Graciete Oliveira Vieira
    Citation: BMC Pediatrics 2025 25:173
    Content type: Research Published on:

  32. Few data are available on the interplay of antenatal and early inhaled postnatal corticosteroids. The NEuroSIS trial randomized extremely preterm infants to receive either early inhaled budesonide or placebo a...

    Authors: Jehudith Fontijn, Corinna Engel, Karen B. Kreutzer, Christian Poets and Dirk Bassler
    Citation: BMC Pediatrics 2025 25:172
    Content type: Research Published on:

  33. Kawasaki disease (KD), also known as mucocutaneous lymph node syndrome, is an acute febrile exanthematous illness primarily affecting children under 5 years of age. It is characterized by systemic vasculitis o...

    Authors: Zhiwei Zhu, Kai Tan, Hui Wang, Zhenyu Liu, Yonghua Yuan, Xuan Xu, Liping Liu, Jie Wen, Yu Liu and Keji Ling
    Citation: BMC Pediatrics 2025 25:171
    Content type: Case Report Published on:

  34. Allergic rhinitis (AR) is a disease that has significant effects on the quality of life of people and exhibits different phenotypic features with different clinical findings. By analyzing the data of pediatric...

    Authors: Damla Baysal Bakır, Halime Yağmur, Gizem Kabadayı, Özge Kangallı Boyacıoğlu, Özge Atay, Suna Asilsoy and Nevin Uzuner
    Citation: BMC Pediatrics 2025 25:170
    Content type: Research Published on:

  35. In the Malaysian primary healthcare setting, neonatal jaundice (NNJ) screening uses either Kramer’s Rule (KR), a visual assessment, or a combination with non-invasive transcutaneous bilirubin (TcB). However, d...

    Authors: Xin-Jie Lim, Subashini Ambigapathy, E-Li Leong, Lili Zuryani Marmuji, Ai-Ping Phan, Farah Aishah Hamdan, Sheela Mithra Nandi Mithra, Nurul Idayu Mior Azmi, Philip Rajan Devesahayam and Jeyaseelan P. Nachiappan
    Citation: BMC Pediatrics 2025 25:169
    Content type: Research Published on:

  36. The My Positive Health (MPH) dialogue tool for children was developed to aid children and teenagers in reflecting and communicating about their health from a broader perspective. This study investigates facili...

    Authors: S. de Jong-Witjes, E. E. Berkelbach van der Sprenkel, M. C. Kars, M. Huber, S. L. Nijhof, R. Nuboer, D. M. Broekhuijsen-van Henten, C. A. Lasham, E. G.A.H. van Mil and E. M. van de Putte
    Citation: BMC Pediatrics 2025 25:168
    Content type: Research Published on:

  37. Meconium aspiration syndrome is a life-threatening respiratory disease due to the aspiration of meconium-stained amniotic fluid into the lungs, resulting in neonatal morbidity and mortality. Impacts of meconiu...

    Authors: Marta Adugna, Kibret Asmare and Amare Wondim
    Citation: BMC Pediatrics 2025 25:167
    Content type: Research Published on:

  38. The study investigates the impact of age at initial diagnosis on the prognosis of pediatric hepatoblastoma (HB) patients, aiming to provide a basis for optimizing risk stratification.

    Authors: Zhen Li, Hong Jiang, Yuan-Qi Wang, Wen-Qing Wang, Li-Bin Huang, Jun-Cheng Liu and Hong-Man Xue
    Citation: BMC Pediatrics 2025 25:166
    Content type: Research Published on:

  39. This study investigates the potential of the pan-immune-inflammation values (PIV) index as a biomarker for diagnosing acute appendicitis in children and compares its performance with other systemic inflammator...

    Authors: Nurcan Çoşkun, Mehmet Metin, Gül Doğan, Hülya İpek, Emre Demir and Çağatay Evrim Afşarlar
    Citation: BMC Pediatrics 2025 25:165
    Content type: Research Published on:

  40. Difficulties in microbiologically confirming childhood tuberculosis (TB) can result in delayed treatment and increased disease severity.

    Authors: Shuting Quan, Xue Tian, Yuting Sun, Hui Qi, Weiwei Jiao, Baixu Sun, Fang Xu, Min Fang, Xuemei Yang, Xi Zeng, Kun Duan, Jichao Wang, Xue Fu, Li Duan, Lin Sun and Adong Shen
    Citation: BMC Pediatrics 2025 25:164
    Content type: Research Published on:

  41. Pediatric acute liver failure (PALF) is a life-threatening condition with no definitive treatment. This study evaluated the combined use of the dual plasma molecular adsorption system (DPMAS) and plasma exchan...

    Authors: Jia-Hao Geng, Shi-Lin Liu, Bao-Fan Dou, Jun-Lin Zhao, He-Kai Ma, Zhi-Yuan Wang and Shu-Jun Li
    Citation: BMC Pediatrics 2025 25:163
    Content type: Research Published on:

  42. The purpose of this study was to investigate: (1) the incidence of cardiopulmonary complications within 30 days after surgery in pediatric patients with preoperative Omicron variants infection, (2) the mortali...

    Authors: Yan-Yifang Xu, Zhen-Zhen Dai, Han Zhou, Hai Li and Yi Du
    Citation: BMC Pediatrics 2025 25:162
    Content type: Research Published on:

  43. Previous studies have demonstrated that paternal involvement in childcare for infants up to 6 months of age can prevent injuries in children up to 18 months of age. However, the relationship after 18 months of...

    Authors: Kanako Shimada, Akiko Tsuchida, Haruka Kasamatsu, Tomomi Tanaka, Kenta Matsumura and Hidekuni Inadera
    Citation: BMC Pediatrics 2025 25:161
    Content type: Research Published on:

  44. Orbital emphysema and pneumocephalus rarely occur without associated skull fractures. Over the past decades, a few case reports have documented compressed air injuries as a rare cause of orbital emphysema and ...

    Authors: Ahmed Bassiouny, Amgad El Nokrashy, Mustafa Al sharabi, Baraa Al-Ashker, Eslam A. Elsery and Aya M. Hashish
    Citation: BMC Pediatrics 2025 25:160
    Content type: Case Report Published on:

  45. Potentially nephrotoxic drugs play an important role in acute kidney injury (AKI) in children. In the previous pharmacovigilance study, we found a statistical correlation between diazepam and AKI in children, ...

    Authors: Miao Zhang, Liang Huang, Yu Zhu, Linan Zeng, Guo Cheng, Hailong Li and Lingli Zhang
    Citation: BMC Pediatrics 2025 25:159
    Content type: Research Published on:

  46. Developmental delay in early childhood is a significant concern with multifaceted causes and implications. The Bayley Scales of Infant and Toddler Development (BSID-III) is widely used for developmental assess...

    Authors: Mehran Karimi, Alireza Emarati, Zahra Nafei, Farimah Shamsi, Niloofar Gashty Mazar and Elahe Akbarian
    Citation: BMC Pediatrics 2025 25:158
    Content type: Research Published on:

  47. Studies on procalcitonin (PCT) for identifying sepsis were published as early as 1993 and since then, PCT has been the topic of over 8,500 studies. Several studies show PCT to be superior to CRP in differentia...

    Authors: Dorine M. Borensztajn, Joany M. Zachariasse, Enitan D. Carrol, Ruud G. Nijman, Ulrich von Both, Marieke Emonts, Jethro Herberg, Benno Kohlmaier, Michael Levin, Emma Lim, Ian K. Maconochie, Federico Martinón-Torres, Marko Pokorn, Irene Rivero-Calle, Aleksandra Rudzāte, Chantal D. Tan…
    Citation: BMC Pediatrics 2025 25:157
    Content type: Research Published on:

  48. Children with obstructive sleep apnea (OSA) can develop cognitive impairments. Urinary adrenaline (EPI), norepinephrine (NE) and gamma-aminobutyric acid (GABA) are elevated, and taurine is decreased in childre...

    Authors: Jiapeng Ji, Yuqing Wang, Bolin Chen, Xueyun Xu and Meng Lv
    Citation: BMC Pediatrics 2025 25:156
    Content type: Research Published on:

  49. Uvulectomy is a surgical procedure that involves the removal or excision of part of the uvula, the small, fleshy tissue that hangs down at the back of the throat. This procedure is traditionally practiced in v...

    Authors: Gali Nega, Tamiru Hailu and Muluemebet Abera
    Citation: BMC Pediatrics 2025 25:155
    Content type: Research Published on:
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BMC Pediatrics

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