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  1. Oral propranolol is the first-line treatment for Infantile hemangioma (IH). However, there is a lack of studies indicating whether the congenital heart disease (CHD) makes a difference in oral propranolol ther...

    Authors: Junsong Yu, Tao Lei, Lu Gao, Zhihong Huang, Yang Bi, Yun He and Wei Feng
    Citation: BMC Pediatrics 2025 25:354
  2. During the coronavirus disease 2019 (COVID-19) pandemic, healthcare facilities developed surveillance systems to identify patients suspected of having COVID-19 to segregate them during their hospital stay. As ...

    Authors: Ayesha Imtiaz, Abdullah Y. Akkam, Lulwah H. AlThumali, Ahlam M. AlHarthi, Honey G. Porte, Wesal S. AlOsaimi, Maha M. A. AlAsmari, Rawda B. G. Salih and Biswadev Mitra
    Citation: BMC Pediatrics 2025 25:352
  3. Tic disorder (TD) is a diverse neurodevelopmental disorder with various symptoms and comorbidities. Traditional classifications based on age onset and duration fail to adequately characterize the full clinical...

    Authors: Kai Yang, Wenyan Zhang, Ying Li, Xianbin Wang, Zhongliang Jiang, Shujin Hu, JinHyun Jun, Qinghao Yang, Jingyi Li, Xu Hong, Yonghua Cui and Tianyuan Lei
    Citation: BMC Pediatrics 2025 25:349
  4. There exist multiple extraintestinal manifestations of inflammatory bowel disease. The most common are arthritis, aphthous stomatitis, or uveitis. Aseptic abscess syndrome is not usually included among these e...

    Authors: Martina Ambrozová, Matěj Hrunka, Marta Ježová, Milan Urík and Petr Jabandžiev
    Citation: BMC Pediatrics 2025 25:346
  5. T1 Diabetes (T1D) is one of the most common chronic diseases in children and young people [1] with almost 34 000 aged 18 years or less living with T1D [2]. Physical activity is promoted as one of a number of mana...

    Authors: Emma J. Cockcroft, Dillon Chithuranjan, Parth Narendran, Robert C. Andrews and Renuka P. Dias
    Citation: BMC Pediatrics 2025 25:345
  6. Meckel’s diverticulum (MD) is the most common congenital anomaly of the small intestine, and often leads to various complications in children. This study aims to compare the efficacy and safety of single-incis...

    Authors: Zhuojun Xie, Wei Feng, Xiaohong Die, Jinping Hou, Zhenhua Guo, Wei Liu, Yi Wang and Shasha Tian
    Citation: BMC Pediatrics 2025 25:344
  7. Low birth weight continues to be a significant cause of perinatal morbidity and mortality, contributing to 80% of neonatal deaths in low and middle-income countries. To the authors’ knowledge, no prior study h...

    Authors: Kusse Urmale Mare, Gashaye Gobena Andarge, Kebede Gemeda Sabo, Osman Ahmed Mohammed, Ahmed Adem Mohammed, Abdulkerim Hassen Moloro, Oumer Abdulkadir Ebrahim, Beminate Lemma Seifu, Bizunesh Fantahun Kase, Habtamu Solomon Demeke, Temesgen Gebeyehu Wondmeneh, Setognal Birara Aychiluhm, Abay Woday Tadesse, Getahun Fentaw Mulaw, Simeon Meskele Leyto, Begetayinoral Kussia Lahole…
    Citation: BMC Pediatrics 2025 25:342
  8. Insufficient food intake and infectious diseases cause undernutrition. Undernutrition in children is a severe public health issue globally, especially in low-resource areas. Among the most vulnerable to these ...

    Authors: Tesfaye Shibiru and Anthonisamy Arulandhu
    Citation: BMC Pediatrics 2025 25:341
  9. Decreased SIRT1 exhibits a correlation with a range of cardiovascular diseases. However, the changes in serum SIRT1 levels in pediatric primary hypertension have not been reported. This study aimed to investig...

    Authors: Yuting Wang, Yao Lin, Hui Wang, Yaqi Li, Chen Shen and Lin Shi
    Citation: BMC Pediatrics 2025 25:340
  10. Necrotizing enterocolitis (NEC) is a serious condition mainly affecting newborns, especially preterm or low birth weight ones, with a poor prognosis. The present study aimed to comprehensively evaluate the dia...

    Authors: Li Ren, Mingyan Hei, Hailan Wu, Dan Guo, Shiqi Liu, Qiaoru Zhang and Min Jiang
    Citation: BMC Pediatrics 2025 25:338
  11. This study aims to reveal the composition and features of the gut microbiota in neonatal hemolytic jaundice, potentially identifying biomarkers for the diagnosis of this condition.

    Authors: Jin Huang, Bi Zhou, Feng Zhu, Ying Li, Yingying Li, Rui Zhang, Jingling Zhang and Lili Wang
    Citation: BMC Pediatrics 2025 25:337
  12. Complicated appendicitis is one of significant pediatric surgical care challenges and its burden varied from 5 to 75%. However, there is limited study about prevalence of complicated appendicitis among childre...

    Authors: Molla Azmeraw, Biruk Beletew Abate, Dessie Temesgen, Sefineh Fenta Feleke, Ribka Nigatu Haile, Melsew Dagne Abate and Tegene Atamenta Kitaw
    Citation: BMC Pediatrics 2025 25:336
  13. To compare the characteristics, functional levels, and comorbidities of children with ataxic cerebral palsy (CP), with those of children with other CP subtypes.

    Authors: Katina Pettersson, Mette Johansen, Reidun Jahnsen and Elisabet Rodby-Bousquet
    Citation: BMC Pediatrics 2025 25:335
  14. The aim of our research was to explore the distribution characteristics of the most common food and inhalant allergens in children from Foshan city in Southwest China to provide evidence for the development of...

    Authors: Xiao-Wen Yuan, De bing Huang, Guang-Rong Feng, Hui-Ling Ye, Ping Chen and Jie Yao
    Citation: BMC Pediatrics 2025 25:334
  15. Pulmonary mucinous adenocarcinoma without congenital pulmonary airway malformation (CPAM) is extremely rare in pediatric patients. Here, we report a unique case of minimally invasive mucinous adenocarcinoma wi...

    Authors: Ping Zhou, Cuomu Zhaxi and Lili Jiang
    Citation: BMC Pediatrics 2025 25:333
  16. As the survival rate of preterm infants continues to rise worldwide, more infants are at risk of developing sight-threatening retinopathy of prematurity (ROP). Destructive retinal laser treatment and intravitr...

    Authors: Ann Hellström, Mariya Petrishka-Lozenska, Aldina Pivodic, Anders K. Nilsson, Ulrika Sjöbom, Ingrid Hansen Pupp, David Ley, Lotta Gränse, Hanna Maria Öhnell, Gunnar Jakobsson, Karin Sävman, Lois E. H. Smith and Pia Lundgren
    Citation: BMC Pediatrics 2025 25:332
  17. Adenovirus infection causes considerable morbidity and mortality in pediatric patients, primarily those affected by severe respiratory system involvement. Although prevalent, it often presents vague indication...

    Authors: Xiaofen Tao and Sheng Ye
    Citation: BMC Pediatrics 2025 25:331
  18. To evaluate the current evidence on the diagnosis, management, and outcomes of pediatric pulmonary embolism (PE) across varying severity classifications, including massive, submassive, and non-massive presenta...

    Authors: Mohammed Alsabri, Dina Essam Abo-elnour, Mohammed Ayyad, Mahmoud Shaaban Abdelgalil, Basel F. Alqeeq and Muhammad Azan Shahid
    Citation: BMC Pediatrics 2025 25:330
  19. Care maps are a caregiver-created diagrammatic tool to support the care of children with medical complexity (CMC). They provide a high-level overview of care, allowing the care team to appreciate the interrela...

    Authors: Sherri Adams, Madison Beatty, Blossom G. Dharmaraj, Clara Moore, Arti D. Desai, Leah Bartlett, Erin Culbert, Eyal Cohen, Jennifer N. Stinson and Julia Orkin
    Citation: BMC Pediatrics 2025 25:329
  20. Evidence suggests that parents/carers of autistic children have lower subjective physical and mental health which in turn can affect their overall quality of life (QoL). The aim of this study was to determine ...

    Authors: James Rufus John, Christa Lam-Cassettari, Cheryl Dissanayake and Valsamma Eapen
    Citation: BMC Pediatrics 2025 25:326
  21. The global prevalence of myopia among children has considerably increased over the past few decades, affecting the children’s eye health and quality of life. According to the inconsistent reports of myopia amo...

    Authors: Nader Salari, Saba Molaeefar, Amir Abdolmaleki, Mahan Beiromvand, Masoud Bagheri, Shabnam Rasoulpoor and Masoud Mohammadi
    Citation: BMC Pediatrics 2025 25:325
  22. Congenital heart disease (CHD) affects approximately 1% of newborns and is a leading cause of mortality in early childhood. Despite the importance of early detection, current screening methods, such as pulse o...

    Authors: Yu-Shin Lee, Hung-Tao Chung, Jainn-Jim Lin, Mao-Sheng Hwang, Hao-Chuan Liu, Hsin-Mao Hsu, Ya-Ting Chang and Syu-Jyun Peng
    Citation: BMC Pediatrics 2025 25:324
  23. Impaired height is a common complication of 21-hydroxylase deficiency (21OHD), yet sensitive monitoring indicators remain limited. This study aims to elucidate growth characteristics and identify effective mon...

    Authors: Hemeng Chong, Yalei Pi, Yanan Zhang, Yuqian Li, Yutong Xing and Huifeng Zhang
    Citation: BMC Pediatrics 2025 25:323
  24. Children with severe constipation often require disimpaction when standard treatments fail, typically involving high doses of oral laxatives or rectal enemas. Practice guidelines for nurses lack clear directiv...

    Authors: Marion A. Meester–Soonius, Brigitha W. Nuijens, Roy S. Koendering, Inge Ertugrul–van der Graaf and Elvira K. George
    Citation: BMC Pediatrics 2025 25:322
  25. Nocturnal enuresis represents a persistent pediatric health challenge characterized by variable treatment responses. Despite established therapeutic interventions, a substantial proportion of children fail to ...

    Authors: Parsa Lorestani, Alireza Khodadadiyan, Mohammad Amin Kaviari, Alireza Montazeri, Hadi Golmoradi, Amir Mohammad Lorestani and Mohamad Reza Tohidi
    Citation: BMC Pediatrics 2025 25:321
  26. Full immunisation of children by their first birthday is a crucial public health target. Vaccines protect children from preventable diseases, promoting individual and community health. In Sierra Leone, a count...

    Authors: Augustus Osborne, Camilla Bangura, Umaru Sesay and Bright Opoku Ahinkorah
    Citation: BMC Pediatrics 2025 25:320
  27. Colostomy is an important emergency procedure to save children’s lives. It is necessary to use a suitable educational program to improve the knowledge and caring performance of parents. Therefore, this study w...

    Authors: Ashrafalsadat Hakim, Sara Kazemi, Mehran Peyvasteh and Mohammad Hossein Haghighizadeh
    Citation: BMC Pediatrics 2025 25:319
  28. Vaccination is essential for building immunity across various populations, and governments consider it a cornerstone of public health. This study aims to investigate the prevalence of gelatin allergy among inf...

    Authors: Mehdi Shokri, Masoud Movahedi, Nima Parvaneh, Mohammad Gharagozlou, Mohadese Sadat Mousavi Khorshidi, Muhadese Mahdavi and Fatemh Alizadeh
    Citation: BMC Pediatrics 2025 25:318
  29. The aim of this study is to evaluate the predictive value of the vasoactive inotropic score (VIS) for mortality in extremely low birth weight (ELBW) preterm infants and to compare this value with the well-know...

    Authors: Elif Özalkaya, İlter Arifoğlu, Emre Yarış, Sevilay Topcuoğlu, Selim Sancak, Emre Dinçer, Özge Yatır Alkan and Güner Karatekin
    Citation: BMC Pediatrics 2025 25:317
  30. Despite notable global reductions in infant and under-five mortality over the last two decades, about half of the remaining neonatal deaths occur among low birth weight (LBW) infants. We conducted a prospectiv...

    Authors: Tisungane Mvalo, Sangappa M. Dhaded, Karim P. Manji, Linda Vesel, Katherine E.A. Semrau, Rodrick Kisenge, Sarah Somji, Msandeni Chiume, Friday Saidi, Irving F. Hoffman, Sunil Vernekar, Roopa Bellad, Bhavana Koppad, Danielle E. Tuller, Rana Mokhtar, Anne C.C. Lee…
    Citation: BMC Pediatrics 2025 25:316
  31. Leukocyte adhesion deficiency III (LAD III) is a very rare autosomal recessive primary immunodeficiency characterized by recurrent infections without pus formation and bleeding syndrome of Glanzmann-type and l...

    Authors: Zahra Chavoshzadeh, Samin Sharafian, Samin Alavi, Minoo Ahmadinejad, Negar Shams, Fatemeh Malek and Mohammad Saberi
    Citation: BMC Pediatrics 2025 25:315
  32. Numerous systematic reviews have shown home visiting interventions to be effective at improving a variety of parent and child outcomes. No review has, however, examined the impact of home visiting programs tar...

    Authors: Sara Cibralic, Weng Tong Wu, Bright Opoku Ahinkorah, Christa Lam-Cassettari, Susan Woolfenden, Jane Kohlhoff, Rebekah Grace, Lynn Kemp, Patrice Johnson, Elisabeth Murphy, April Deering, Shanti Raman and Valsamma Eapen
    Citation: BMC Pediatrics 2025 25:314
  33. Hirschsprung’s disease (HSCR) is a congenital gastrointestinal disorder. Pull-through (PT) surgery, the primary treatment, often leads to recurrent constipation. The causes of redo pull-through (redo-PT) for r...

    Authors: Jun Xiao, Shimin Yang, Lei Xiang, Bo Qin, Jingyi You, Mei Dong, Youshan Xie, Xuan Zhang, Xuyong Chen, Zejian Li, Honglin Li and Jiexiong Feng
    Citation: BMC Pediatrics 2025 25:313
  34. Nail-biting or onychophagia is a common phenomenon affecting children. Excessive nail biting is associated with several adverse consequences beyond mere appearance. The aim of this study is to evaluate the eff...

    Authors: Zohour Ibrahim Rashwan, Hamida Ahmed Mostafa Darweesh, Fatma Ahmed Elsobky, Samah Abdallah Mohamed Amer and Mabrouka Attia Ali Nada
    Citation: BMC Pediatrics 2025 25:312
  35. Healthcare practitioners require a robust predictive system to accurately diagnose diseases, especially in young children with conditions such as anemia. Delays in diagnosis and treatment can have severe conse...

    Authors: Ali Yimer, Hassen Ahmed Yesuf, Sada Ahmed, Alemu Birara Zemariam, Endris Mussa, Nurye Sirage, Adem Yesuf and Abdulaziz Kebede Kassaw
    Citation: BMC Pediatrics 2025 25:311
  36. The neonatal period is the most dangerous time during which the newborn challenges the highest risk of death. This study aimed to develop a validated questionnaire to assess the knowledge of the population abo...

    Authors: Esraa Abdellatif Hammouda, Suzan Abdel-Rahman, Marwa Abdelwahab Hassan, Marwa Abdelkarim, Engy Saad Abdelmoneim Elkaragy, Ayed A. Shati and Ramy Mohamed Ghazy
    Citation: BMC Pediatrics 2025 25:309
  37. Gastrointestinal (GI) manifestations have been reported as the most extra-pulmonary manifestations of coronavirus disease 2019 (COVID-19). Recognizing the various manifestations, especially as presenting sympt...

    Authors: Reza Sinaei, Ali Hosseininasab, Parvin Abbaslou, Mazyar Zeinali, Elham Iranmanesh, Roya Sinaei and Keramat Rahmanian
    Citation: BMC Pediatrics 2025 25:308
  38. Nutritional rickets is a preventable skeletal disorder caused by deficiencies in vitamin D, calcium, or phosphate, leading to softening and weakening of bones. While it was once nearly eliminated in high-incom...

    Authors: Helen Abebe, Berhe Gebremichael, Assefa Desalew, Melat B. Maruta, Addis Eyeberu, Jemal Ahmed Nure, Adera Debella, Lemma Demissie Regassa and Ibsa Mussa
    Citation: BMC Pediatrics 2025 25:306
  39. Alterations in insulin sensitivity in the fetus during pregnancy have been associated with IUGR and future increases in sweet food cravings.

    Authors: Liliana Yanet Gómez Aristizábal, Susana Cararo Confortin, Juliana Ramos Carneiro, Cecilia Claudia Costa Ribeiro, Rosângela Fernandes Lucena Batista, Maria Teresa Seabra Soares de Britto e Alves, Vanda Maria Ferreira Simões and Antônio Augusto Moura da Silva
    Citation: BMC Pediatrics 2025 25:305

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