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Pediatric clinical trials face many challenges that hinder the development of safe and effective pediatric drugs. Enhancing risk control and management quality of pediatric clinical trials in research centers ...
The purpose of this meta-analysis was to systematically review studies in the literature that evaluated the effect of different exercise programs on blood pressure in overweight children and adolescents.
This study aimed to assess the link between polymorphisms in the SLCO1B1 gene, responsible for the organic anion transporter polypeptide 1B1 (OATP1B1), and the risk of neonatal hyperbilirubinemia.
Bronchiolitis obliterans syndrome (BOS) represents a significant source of morbidity and non-relapse mortality among children and young adults treated with allogeneic hematopoietic stem cell transplantation (a...
This study aims to characterize and analyze the expression of representative biomarkers like lymphocytes and immune subsets in children with thyroid disorders. It also intends to develop and evaluate a machine...
The COVID-19 vaccination has played a crucial role in combating the pandemic, yet vaccine hesitancy remains a significant barrier to achieving herd immunity. This challenge is particularly pronounced in specif...
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurological disorders, especially in childhood. Children with ADHD may have symptoms such as an inability to maintain concentration an...
Cerebral vasculopathy is a frequent and serious complication of major sickle cell disease syndromes. Transcerebral Doppler (TCD) can detect stenosis of the main arteries at the base of the skull before stroke ...
Decorative crystal balls, also known as superabsorbent polymer gel beads, pose a significant hazard when ingested due to their ability to expand upon exposure to water. Diagnosing crystal ball ingestion remain...
Approximately 100 capsular serotypes of S. pneumonia have been identified according to the composition of their capsular polysaccharides, currently available vaccines do not cover many of these. Pneumococcal vacc...
In the history of Neonatology, decades ago pain has been little studied because it was believed that newborns didn’t have the capacity to experience pain. Nowadays, there is enough evidence for the existence o...
This study aims to evaluate the efficacy and safety of Etanercept and Adalimumab in the treatment of polyarticular juvenile idiopathic arthritis (pJIA).
Atopic dermatitis (AD) is the most common chronic skin disease in children. It adversely affects child’s physical health, daily functioning, and overall quality of life (QoL), impacting not only the child but ...
To examine the changes in influenza types (A/B), including influenza A subtypes (A(H1N1) / A(H3N2)) and influenza B lineages (B/Victoria and B/Yamagata) in children in Hangzhou City, China.
Nusinersen was the first approved disease modifying therapy (DMT) for spinal muscular atrophy (SMA). Intrathecal administration of nusinersen enables drug delivery directly to the central nervous system, where...
Primary hypertrophic osteoarthropathy (PHO) is a rare genetic disorder primarily characterized by digital clubbing, pachydermia, and periostitis. The rarity of this disease often leads to misdiagnosis or delay...
Previous studies have suggested that probiotics may have potential benefits for preterm infants. Their efficacy seems to depend on the particular species or combinations used.
Smoking is a risk factor for cardiovascular complications and can promote a severe course of COVID-19 infection. The aim of this study was to compare smoking habits of young people with diabetes with the gener...
Motor competence and executive function skills develop actively at preschool age. Both are important for socialization, school achievements, and well-being. However, the association between motor competence an...
Hemorrhagic cystitis (HC) is a common complication of hematopoietic stem cell transplantation (HSCT) and may adversely affect the prognosis of patients. However, the risk factors associated with HC and its inf...
Intussusception is the leading cause of acute abdominal conditions in infants, yet it is frequently under-recognised in those younger than 3 months, potentially resulting in serious complications such as bowel...
The original article was published in BMC Pediatrics 2025 25:189
Nocturnal enuresis (NE) is a prevalent pediatric condition with significant physical, psychological, and social impacts. This study aimed to determine the prevalence of NE among primary school children in Pale...
Hormones are molecules that contribute significantly to mental and physical health due to their role in emotion regulation (ER) processes. However, the role and effect of hormones on the ER has not yet been fu...
Infant formula with human milk oligosaccharides (HMOs) and increased β-palmitate mimics breast milk nutritional composition and clinical benefits. We aimed to assess formula-fed infant growth, gastrointestinal...
Anorectal malformations and Hirschsprung’s disease are congenital conditions impacting the digestive system, with a particularly uncommon co-occurrence, estimated at 2–3% of all ARM cases. This case series exp...
Central venous catheterization is crucial for the perioperative and postoperative management of neonatal cardiac surgery patients. The procedure can be challenging due to the small size of the vessels, and it ...
This study used latent class analysis (LCA) to examine the potential patterns of unhealthy lifestyle factors (ULFs) and their association with overweight and obesity in children and adolescents with overweight...
The objective of this study was to assess the validity and reliability of the European Health Literacy Scale Child Form in Turkish children and to examine the instrument’s psychometric properties.
To evaluate the clinical utility of targeted next-generation sequencing (tNGS) for pathogen detection of pediatric acute lower respiratory tract infections (ALRTIs), with a particular focus on the use of throa...
Obesity is the largest global public health epidemic, increasingly affecting children and adolescents. Studies suggest that genetic markers such as single nucleotide polymorphisms (SNPs) may be associated with...
The original article was published in BMC Pediatrics 2024 24:615
Kangaroo mother care (KMC) is recommended as a beneficial intervention to promote the wellbeing of preterm infants. This study evaluated the effect of KMC on anthropometric indexes in preterm newborns, with an...
Altered gut microbiota (GM) profiles have been documented in children with food allergies (FA) and experiencing malnutrition. This study explored the GM composition in children with FA across varying degrees o...
Histologically, our understanding of intestinal polyps remains limited in scope, particularly regarding the diverse subtypes observed in pediatric patients. To enhance our comprehension, three different polyp ...
Balance dysfunction exists in children with hearing loss, especially sensorineural loss, impacting on cognitive development, socio-emotional development and literacy. However, there is limited assessment of ba...
The acronym STORCH encompasses gestational infections that can lead to congenital syndromes or adverse neurological outcomes in children. In Brazil and worldwide, there has been an alarming increase in confirm...
The present study aimed to investigate the positive rate of adolescent idiopathic scoliosis (AIS) among school children in Xiamen, Fujian province, China, and evaluate its possible risk factors.
The role of biological factors such as foetal haemoglobin in modifying the severity of Sickle Cell Anaemia (SCA) has been extensively investigated. However, the phenotypic variability of SCA cannot be explaine...
The assessment of the newborn after birth is fundamental for identifying those requiring resuscitation. Certain components of the Apgar score are used to assess neonatal condition, but their value is insuffici...
Hepatitis B Virus infection is a global health problem. Transplacental maternal antibodies can protect the infant early in life from infection. Objectives: This study investigates the correlation between mater...
To explore the blood level and its change trend of primary and secondary school students aged 6 ~ 18 years in high altitude area (4300 m above sea level), and to provide a reference basis for the establishment...
Pediatric epilepsy presents challenges in treatment optimization, with a significant proportion of patients experiencing inadequate seizure control despite anti-seizure medications (ASMs) therapy. Recent resea...
The present study aimed to analyze the risk factors affecting the prognosis children with fulminant myocarditis.
Umbilical venous catheterization (UVC) is commonly performed in neonates, but improper catheter tip may lead to hepatic complications.
This study aims to explore the characteristics and functional changes of intestinal metabolites in children with obstructive sleep apnea hypopnea syndrome (OSAHS) aged 4–6 years old through metabolomic approac...
Preterm delivery continues to be a major concern in the global health system. Where accessible, mother’s milk is the optimal option for neonate nutrition. In recent years, donor milk as the best substitute for...
Timely diagnosis of malignancies in children is very important. Knowing the clinical manifestations of malignancies help in timely diagnosis. The aim of this study is to investigate the prevalence of musculosk...
Routine childhood vaccination (RCV) has demonstrated its effectiveness, saving millions of lives globally and reducing childhood mortality. However, several factors impede mothers from completing their childre...
A retrospective analysis was conducted to evaluate the clinical characteristics, diagnostic challenges, and management strategies in a child with congenital long QT syndrome (cLQTS) caused by a KCNH2 gene pathoge...
Citation Impact 2023
Journal Impact Factor: 2.0
5-year Journal Impact Factor: 2.4
Source Normalized Impact per Paper (SNIP): 0.972
SCImago Journal Rank (SJR): 0.688
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